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Noradrenaline Signalling

Process Cns

Arousal, vigilance and the physical side of stress. It sets whether the person is alert or wired, and it is the transmitter most directly raised by the stimulants that are commonly stacked alongside these compounds.

Relationships

3 connections

Noradrenaline Signalling increases risk of

Insomnia

Difficulty falling or staying asleep, often with night sweats. Its own problem, and an amplifier for every mood effect above it.

Noradrenaline Signalling stimulates

Locus Coeruleus

The brain's noradrenaline source and its arousal dial. It sets how alert, how startled and how awake the person is, which is why compounds that raise sympathetic drive cost sleep before they cost anything else.

Sympathetic Tone

How hard the fight-or-flight side of the nervous system is running. Androgens raise tyrosine hydroxylase and change adrenergic receptor density, so a compound can lift this without touching mood directly. It is the shared cause behind a cluster people treat as four separate problems: a higher resting pulse, night sweats, a short fuse, and sleep that will not come.